Home Diseases and Health Information  

Home Home Translating Report News Physicians Diseases Body Sites Diseases and Health Information Search


This is a broad clinical and histologic category of diseases. The major mucinoses are listed below. Mucin is a common secondary finding in many disorders of the skin, both benign and malignant. Lupus erythematosus, for example, classically has abundant dermal mucin. The following list showcases some of the primary mucinosis.

Generalized myxedema
Pretibial myxedema
Reticular erythematous mucinosis
Papular mucinosis
Acral persistent papular mucinosis
Focal mucinosis
Digital mucous cyst
Cutaneous myxoma
Cutaneous mucinosis of infancy
Nevus mucinosis
Alopecia mucinosa (Follicular mucinosis)

Secondary Mucinosis
Degos disease
Granuloma annulare
Jessner's lymphocytic infiltrate
Lupus erythematosus


Disease Associations  
Other Diagnostic Testing
Gross Appearance and Clinical Variants  
Histopathological Features and Variants  
Special Stains/
Electron Microscopy
Differential Diagnosis  
Commonly Used Terms  
Internet Links  

Self-healing juvenile cutaneous mucinosis: cases highlighting subcutaneous/fascial involvement.

Department of Dermatology, University of North Carolina Hospitals, Chapel Hill, NC, USA.


J Am Acad Dermatol. 2006 Dec;55(6):1036-43. Abstract quote

BACKGROUND: Self-healing juvenile cutaneous mucinosis is a rare disease affecting young people characterized by transient cutaneous lesions and sometimes mild inflammatory symptoms. The deep dermal and subcutaneous features of this disorder have not yet been well described.

OBJECTIVE: The purpose of our study was to present 3 cases of self-healing juvenile cutaneous mucinosis in which the histopathologic features caused diagnostic confusion between this disorder and proliferative fasciitis.

METHODS: The study includes clinical and histologic findings of 3 patients, complemented by a literature review. RESULTS: The histologic descriptions of nodular lesions in self-healing juvenile cutaneous mucinosis reveal features of proliferative fasciitis, including a myxoid stroma and gangliocyte-like giant cells.

LIMITATIONS: Self-healing juvenile cutaneous mucinosis is a rare condition and has not been frequently reported in medical literature. Our findings are based on the pathologic features of 3 patients.

CONCLUSIONS: Our findings further elucidate the histologic features of self-healing juvenile cutaneous mucinosis and expand the differential diagnosis for entities in which gangliocyte-like giant cells are noted.

Macpherson and Pincus. Clinical Diagnosis and Management by Laboratory Methods. Twentyfirst Edition. WB Saunders. 2006.
Rosai J. Ackerman's Surgical Pathology. Ninth Edition. Mosby 2004.
Sternberg S. Diagnostic Surgical Pathology. Fourth Edition. Lipincott Williams and Wilkins 2004.
Robbins Pathologic Basis of Disease. Seventh Edition. WB Saunders 2005.
DeMay RM. The Art and Science of Cytopathology. Volume 1 and 2. ASCP Press. 1996.
Weedon D. Weedon's Skin Pathology Second Edition. Churchill Livingstone. 2002
Fitzpatrick's Dermatology in General Medicine. 6th Edition. McGraw-Hill. 2003.
Weiss SW and Goldblum JR. Enzinger and Weiss's Soft Tissue Tumors. Fourth Edition. Mosby 2001.

Commonly Used Terms

Alcian blue-Common stain used at pH 2.5 to demonstrate mucin.

Colloidal iron-Common stain used to demonstrate mucin.

Glycosaminoglycans-Acid mucopolysaccharides present in the dermis. Produced by fibroblasts and bind minerals and water.

Hyaluronic acid -One type of glycosaminoglycan, unattached to proteins.

Proteoglycans-Glycosaminoglycans attached to proteins.

Basic Principles of Disease
Learn the basic disease classifications of cancers, infections, and inflammation

Commonly Used Terms
This is a glossary of terms often found in a pathology report.

Diagnostic Process
Learn how a pathologist makes a diagnosis using a microscope

Surgical Pathology Report
Examine an actual biopsy report to understand what each section means

Special Stains
Understand the tools the pathologist utilizes to aid in the diagnosis

How Accurate is My Report?
Pathologists actively oversee every area of the laboratory to ensure your report is accurate

Got Path?
Recent teaching cases and lectures presented in conferences

Internet Links

Last Updated December 7, 2006

Send mail to The Doctor's Doctor with questions or comments about this web site.
Read the Medical Disclaimer.

Copyright © The Doctor's Doctor