This is a rare cutaneous mucinosis characterized by multiple small papules on the upper extremities and trunk occurring in infants. Under the microscope, there is mucin in the papillary dermis with no fibroblastic proliferation and scattered chronic inflammatory cells. Some investigators speculate that this a connective tissue nevus similar to nevus mucinosis. However, there is growing consenus that this disease is a variant of lichen myxedematosus (localized scleromyxedema) and has been renamed papular mucinosis of infancy.
Epidemiology Disease Associations Pathogenesis Laboratory/Radiologic/
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Gross Appearance and Clinical Variants Histopathological Features and Variants Special Stains/
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EPIDEMIOLOGY CHARACTERIZATION SYNONYMS INCIDENCE/
AGE SEX GEOGRAPHY EPIDEMIOLOGIC ASSOCIATIONS
DISEASE ASSOCIATIONS CHARACTERIZATION
CHARACTERIZATION RADIOLOGIC LABORATORY MARKERS
CHARACTERIZATION GENERAL VARIANTS
HISTOLOGICAL TYPES CHARACTERIZATION GENERAL
CHARACTERIZATION SPECIAL STAINS IMMUNOPEROXIDASE ELECTRON MICROSCOPY
DIFFERENTIAL DIAGNOSIS KEY DIFFERENTIATING FEATURES DERMAL MUCINOSIS SELF-HEALING JUVENILE CUTANEOUS MUCINOSIS
- J Am Acad Dermatol. 2006 Dec;55(6):1036-43. Abstract quote
BACKGROUND: Self-healing juvenile cutaneous mucinosis is a rare disease affecting young people characterized by transient cutaneous lesions and sometimes mild inflammatory symptoms. The deep dermal and subcutaneous features of this disorder have not yet been well described.
OBJECTIVE: The purpose of our study was to present 3 cases of self-healing juvenile cutaneous mucinosis in which the histopathologic features caused diagnostic confusion between this disorder and proliferative fasciitis.
METHODS: The study includes clinical and histologic findings of 3 patients, complemented by a literature review. RESULTS: The histologic descriptions of nodular lesions in self-healing juvenile cutaneous mucinosis reveal features of proliferative fasciitis, including a myxoid stroma and gangliocyte-like giant cells.
LIMITATIONS: Self-healing juvenile cutaneous mucinosis is a rare condition and has not been frequently reported in medical literature. Our findings are based on the pathologic features of 3 patients.
CONCLUSIONS: Our findings further elucidate the histologic features of self-healing juvenile cutaneous mucinosis and expand the differential diagnosis for entities in which gangliocyte-like giant cells are noted.
TREATMENT CHARACTERIZATION GENERAL
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Last Updated December 7, 2006
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