We have come a long way from those test tubes and bunsen burners you played with in school. These tests include the routine glucose levels to cutting edge cancer screening tests for prostate cancer. In addition, the pathologist has now moved into the realm of molecular biological testing, screening patients for mutations of susceptibility genes for different cancers like breast cancer.
- Albumin, Ischemia-Modified
- alpha fetoprotein (AFP)
- B-Natriuretic peptide (BNP)
- BRCA1 and BRCA2
- Carbohydrate-deficient transferrin (CDT)
- Cardiac Enzymes
- CCP (Anti-Cyclic Citrullinated Peptide)
- Coenzyme Q10
- C-reactive protein (CRP)
- Cystatin C
- Early Prostate Cancer Antigen (EPCA)
- Electrolyte Panel (sodium, potassium, chloride,bicarbonate)
- Folate (Folic Acid)
- GGT (Gamma glutamyltransferase)
- Lipid Panel
- Liver Panel
- Newborn Screening
- Pregnancy Laboratory Testing (Triple Test)
- PSA (Prostate Specific Antigen)
- Thyroid Panel
- Tumor Markers
Interfering Diseases or Substances that Alter Levels Commonly Used Terms Internet Links
INTERFERING DISEASES OR SUBSTANCES THAT ALTER LEVELS CHARACTERIZATION GADOLINIUM MRI CONTRAST AGENTS Gadolinium Magnetic Resonance Contrast Agents Produce Analytic Interference in Multiple Serum Assays
William L. Roberts, MD, PhD
Am J Clin Pathol 2004;121:282-292 Abstract quote
Gadolinium magnetic resonance contrast agents are known to interfere with some clinical chemistry tests, particularly colorimetric assays for serum calcium.
We studied the effects of 4 agents, gadodiamide, gadoversetamide, gadopentetate dimeglumine, and gadoteridol, for interference with multiple serum assays. Gadodiamide and gadoversetamide produced clinically significant negative interference with colorimetric assays for serum angiotensin-converting enzyme, calcium, and zinc. These agents produced clinically significant positive interference in magnesium and total iron binding capacity assays and both positive and negative interference in iron assays. Gadopentetate dimeglumine produced a negative interference with iron assays, and gadopentetate dimeglumine and gadoteridol produced negative interference with a colorimetric zinc assay.
Caution should be exercised when using colorimetric assays for angiotensin-converting enzyme, calcium, iron, magnesium, total iron binding capacity, and zinc in serum samples from patients who have recently received magnetic resonance contrast agents. In general, gadodiamide and gadoversetamide are more likely to produce a clinically significant interference than gadopentetate dimeglumine and gadoteridol. Likewise, certain analytic methods are more prone to interference, while others not affected.
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Rosai J. Ackerman's Surgical Pathology. Ninth Edition. Mosby 2004.
Sternberg S. Diagnostic Surgical Pathology. Fourth Edition. Lipincott Williams and Wilkins 2004.
Robbins Pathologic Basis of Disease. Seventh Edition. WB Saunders 2005.
DeMay RM. The Art and Science of Cytopathology. Volume 1 and 2. ASCP Press. 1996.
Weedon D. Weedon's Skin Pathology Second Edition. Churchill Livingstone. 2002
Fitzpatrick's Dermatology in General Medicine. 5th Edition. McGraw-Hill. 1999.
Weiss SW and Goldblum JR. Enzinger and Weiss's Soft Tissue Tumors. Fourth Edition. Mosby 2001.
Basic Principles of Disease
Learn the basic disease classifications of cancers, infections, and inflammation
Commonly Used Terms
This is a glossary of terms often found in a pathology report.
Learn how a pathologist makes a diagnosis using a microscope
Surgical Pathology Report
Examine an actual biopsy report to understand what each section means
Understand the tools the pathologist utilizes to aid in the diagnosis
How Accurate is My Report?
Pathologists actively oversee every area of the laboratory to ensure your report is accurate
Recent teaching cases and lectures presented in conferences
Last Updated August 11, 2005
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