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Hematopathology is a major subspecialty of pathology, bridging the gap between the clinical and anatomic pathology. With the tremendous advances seen in molecular biology, the pathologist is able to utilize state of the art technology at the microscope. One of the ways these advances are changing hematology is by the use of fluorescent in-situ hybridization or FISH. Utilizing genetic probes tagged with a fluorescent label, genes may be identified on chromosome segments. These chromosomal abnormalities may have prognostic significance in the diagnosis and treatment of many leukemias and lymphomas.

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Last Updated 7/8/2002

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