This is a 29 year old man with a several month history of weight loss and diarrhea. The biopsy is from the duodenum.
Sections show a relatively preserved crypt-to-villous ratio, with no evidence of atrophy.
The lamina propria shows an increase in cellularity, populated by a mononuclear cell infiltrate of lymphocytes and plasma cells.
No significant architectural distortion of the glands or crypts are noted.
|Many of the villi contain an increase in intraepithelial lymphocytes, extending through the full length of the villi and numbering over 1 lymphocyte per 3-4 enterocytes.|
Another view of the increased intraepithelial lymphocytes.
What is Your Diagnosis?
Last Updated 11/4/2002
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