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Background

Dimples may be a cute trait of your significant other but it sometimes may be a clue to an underlying or associated disease or syndrome.

Outline

Disease Associations
Laboratory/Radiologic/Other Diagnostic Testing
Commonly Used Terms

DISEASE ASSOCIATIONS CHARACTERIZATION
DIMPLES ASSOCIATED WITH ABERRANT POSITIONING DURING FETAL LIFE Arthrogryposis
Metaphyseal chondrodysplasia
Camptomelic dysplasia
Kyphomelic dysplasia
Mesomelic dysplasia
Hypophosphatasia
FACIAL DIMPLES-CHEEKS Familia
FACIAL DIMPLES-CHIN Whistling face syndrome
Simosa craniofacial syndrome
Weaver syndrome
SHOULDER DIMPLES Autosomal dominant dimples
18q deletion syndrome
Trisomy 9p
Russell-Silver syndrome
Popliteal pterygium syndrome
SACRAL DIMPLES Spina bifida
Bloom syndrome
Carpenter syndrome
FG syndrome
Robinow syndrome
Smith-Lemli-Opitz syndrome
Dubowitz syndrome
Zellweger syndrome
X-linked dysmorphic syndrome with mental retardation
OTHER Maternal rubella syndrome
Joubert's syndrome
Caudal dysplasia sequence

 

LABORATORY/RADIOLOGIC/
OTHER TESTS

CHARACTERIZATION
RADIOLOGIC

Indications for imaging cutaneous dimples in the posterior lumbosacral region:

Large dimples >5 mm
Deep dimples
Dimples located > 2.5 cm from anal verge (above the gluteal crease)
Dimples associated with hypertrichosis, hemangiomas, capillary malformations, lipomas, or asymmetric gluteal crease
Dimples in patients with history of meningitis
Dimples in patients with neurologic signs or symptoms

Fitzpatrick's Dermatology in General Medicine. 5th Edition. McGraw-Hill. 1999.
Curr Prob Dermatol 2001;13:249-300.


Commonly Used Terms

Skin


Last Updated 12/21/2001

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The Doctor's Doctor