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Background

This rare tumor of the salivary glands is in the differential diagnosis of clear cell tumors of the salivary glands. It is a recently described tumor

Outline

Epidemiology
Gross Appearance and Clinical Variants
Histopathological Features and Variants
Special Stains/Immunohistochemistry/Electron Microscopy
Differential Diagnosis
Prognosis and Treatment
Commonly Used Terms
Internet Links

EPIDEMIOLOGY CHARACTERIZATION
INCIDENCE <20 cases reported
SEX (M:F)
Female predilection

 

GROSS APPEARANCE/
CLINICAL VARIANTS
CHARACTERIZATION
GENERAL Intraoral minor salivary glands mainly in the base of the tounge and palate
VARIANTS  

 

HISTOLOGICAL TYPES CHARACTERIZATION
GENERAL Am J Surg Pathol 19945;181:74-82

Solid masses, nests, infiltrating cords and single file cells with glycogen rich clear cells and smaller cells with eosinophilic cytoplasm
Mitoses are rare
Variable stromal hyalinization
VARIANTS  

 

SPECIAL STAINS/IMMUNOPEROXIDASE/
OTHER
CHARACTERIZATION
SPECIAL STAINS PAS positive diastase sensitive
IMMUNOPEROXIDASE  

 

DIFFERENTIAL DIAGNOSIS KEY DIFFERENTIATING FEATURES
Clear cell tumors of the salivary glands  

 

PROGNOSIS AND TREATMENT CHARACTERIZATION
PROGNOSTIC FACTORS Relatively short follow-up with less than 10 years but no patients have died from the disease
Recurrence rate of 8%
15% rate of metastasis to regional lymph nodes
TREATMENT Excision

Rosai J. Ackerman's Surgical Pathology. Eight Edition. Mosby 1996.
Sternberg S. Diagnostic Surgical Pathology. Third Edition. Lipincott Williams and Wilkins 1999.


Commonly Used Terms

Salivary Glands


Last Updated 12/4/2001

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