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Background
This rare tumor of the salivary glands is in the differential diagnosis of clear cell tumors of the salivary glands. It is a recently described tumor
Outline
Epidemiology
Gross Appearance and Clinical Variants
Histopathological Features and Variants
Special Stains/Immunohistochemistry/Electron Microscopy
Differential Diagnosis
Prognosis and Treatment
Commonly Used Terms
Internet Links
EPIDEMIOLOGY CHARACTERIZATION INCIDENCE <20 cases reported Female predilection
GROSS APPEARANCE/
CLINICAL VARIANTSCHARACTERIZATION GENERAL Intraoral minor salivary glands mainly in the base of the tounge and palate VARIANTS
HISTOLOGICAL TYPES CHARACTERIZATION GENERAL Am J Surg Pathol 19945;181:74-82
Solid masses, nests, infiltrating cords and single file cells with glycogen rich clear cells and smaller cells with eosinophilic cytoplasm
Mitoses are rare
Variable stromal hyalinizationVARIANTS
SPECIAL STAINS/IMMUNOPEROXIDASE/
OTHERCHARACTERIZATION SPECIAL STAINS PAS positive diastase sensitive IMMUNOPEROXIDASE
DIFFERENTIAL DIAGNOSIS KEY DIFFERENTIATING FEATURES Clear cell tumors of the salivary glands
PROGNOSIS AND TREATMENT CHARACTERIZATION PROGNOSTIC FACTORS Relatively short follow-up with less than 10 years but no patients have died from the disease
Recurrence rate of 8%
15% rate of metastasis to regional lymph nodesTREATMENT Excision Rosai J. Ackerman's Surgical Pathology. Eight Edition. Mosby 1996.
Sternberg S. Diagnostic Surgical Pathology. Third Edition. Lipincott Williams and Wilkins 1999.
Last Updated 12/4/2001
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